Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HCFC2

Gene Name

host cell factor C2

Gene ID

29915

Gene Synonyms

HCF-2; HCF2

ORF Size

1239 bp

RefSeq#

BC006558

Gene Description

HCFC2 encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described.

UniGene ID

Hs.506558

HGNC ID

HGNC:24972