Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DKK3

Gene Name

dickkopf WNT signaling pathway inhibitor 3

Gene ID

27122

Gene Synonyms

REIC; RIG

ORF Size

1053 bp

RefSeq#

BC007660

Gene Description

DKK3 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

UniGene ID

Hs.292156

HGNC ID

HGNC:2893