Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DGCR14

Gene Name

DiGeorge syndrome critical region gene 14

Gene ID

8220

Gene Synonyms

DGCR13; DGS-H; DGS-I; DGSH; DGSI; ES2; Es2el

ORF Size

1431 bp

RefSeq#

BC006542

Gene Description

DGCR14 is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.

UniGene ID

Hs.716675

HGNC ID

HGNC:16817