Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

WHRN

Gene Name

whirlin

Gene ID

25861

Gene Synonyms

CIP98; DFNB31; PDZD7B; USH2D; WI

ORF Size

2724 bp

RefSeq#

BC142614

Gene Description

DFNB31 is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

UniGene ID

Hs.93836

HGNC ID

HGNC:16361