Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DERL2

Gene Name

derlin 2

Gene ID

51009

Gene Synonyms

CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa

ORF Size

720 bp

RefSeq#

BC010890

Gene Description

Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 (PubMed 16449189)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.286131

HGNC ID

HGNC:17943