Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DEGS1

Gene Name

delta 4-desaturase, sphingolipid 1

Gene ID

8560

Gene Synonyms

DEGS; DEGS-1; Des-1; DES1; FADS7; MIG15; MLD

ORF Size

972 bp

RefSeq#

BC000961

Gene Description

DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

UniGene ID

Hs.299878

HGNC ID

HGNC:13709