Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CLCNKA

Gene Name

chloride voltage-gated channel Ka

Gene ID

1187

Gene Synonyms

ClC-K1; CLCK1; hClC-Ka

ORF Size

2064 bp

RefSeq#

BC048282

Gene Description

CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.591533

HGNC ID

HGNC:2026