Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CCDC40

Gene Name

coiled-coil domain containing 40

Gene ID

55036

Gene Synonyms

CILD15; FAP172

ORF Size

3096 bp

RefSeq#

BC035251

Gene Description

CCDC40 encodes a protein that is necessary for motile cilia function. It functions in correct left-right axis formation by regulating the assembly of the inner dynein arm and the dynein regulatory complexes, which control ciliary beat. Mutations in this gene cause ciliary dyskinesia type 15, a disorder due to defects in cilia motility. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.202542

HGNC ID

HGNC:26090