human CARD8 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-204087
Availability:
3-5 weeks
Name:
Ad-h-CARD8
This is an Adenovirus expressing Human CARD8.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CARD8
- Gene Name
- caspase recruitment domain family member 8
- Gene ID
- 22900
- Gene Synonyms
- CARDINAL; DACAR; DAKAR; NDPP; NDPP1; TUCAN
- ORF Size
- 1179 bp
- RefSeq#
- BC056891
- Gene Description
- CARD8 belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
- UniGene ID
- Hs.655940
- HGNC ID
- HGNC:17057
Related Products
Product | Cat No. |
---|---|
AAV-h-CARD8 | AAV-204087 |
AAV-h-CARD8 | AAV-204088 |
Ad-h-CARD8 | ADV-204088 |
AAV-h-CARD8-shRNA | shAAV-204088 |
Ad-h-CARD8-shRNA | shADV-204088 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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