Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NMRK1

Gene Name

nicotinamide riboside kinase 1

Gene ID

54981

Gene Synonyms

bA235O14.2; C9orf95; NRK1

ORF Size

600 bp

RefSeq#

BC001366

Gene Description

Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 (PubMed 15137942)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.494186

HGNC ID

HGNC:26057