Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BIRC2

Gene Name

baculoviral IAP repeat containing 2

Gene ID

329

Gene Synonyms

API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48

ORF Size

1857 bp

RefSeq#

BC028578

Gene Description

BIRC2 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.696238

HGNC ID

HGNC:590