Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

APBB2

Gene Name

amyloid beta precursor protein binding family B member 2

Gene ID

323

Gene Synonyms

FE65L; FE65L1

ORF Size

2211 bp

RefSeq#

BC027946

Gene Description

APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.479602

HGNC ID

HGNC:582