Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AMD1

Gene Name

adenosylmethionine decarboxylase 1

Gene ID

262

Gene Synonyms

ADOMETDC; AMD; SAMDC

ORF Size

1005 bp

RefSeq#

BC000171

Gene Description

AMD1 encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.

UniGene ID

Hs.159118

HGNC ID

HGNC:457