Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AICDA

Gene Name

activation induced cytidine deaminase

Gene ID

57379

Gene Synonyms

AID; ARP2; CDA2; HEL-S-284; HIGM2

ORF Size

597 bp

RefSeq#

BC006296

Gene Description

AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

UniGene ID

Hs.149342

HGNC ID

HGNC:13203