Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ADAM12

Gene Name

ADAM metallopeptidase domain 12

Gene ID

8038

Gene Synonyms

ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA

ORF Size

2214 bp

RefSeq#

BC060804

Gene Description

ADAM12 encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

UniGene ID

Hs.594537

HGNC ID

HGNC:190