Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AASS

Gene Name

aminoadipate-semialdehyde synthase

Gene ID

10157

Gene Synonyms

LKR/SDH; LKRSDH; LORSDH

ORF Size

2778 bp

RefSeq#

BC156456

Gene Description

AASS encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

UniGene ID

Hs.156738

HGNC ID

HGNC:17366