Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AAAS

Gene Name

aladin WD repeat nucleoporin

Gene ID

8086

Gene Synonyms

AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003

ORF Size

1641 bp

RefSeq#

BC000659

Gene Description

AAAS is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.369144

HGNC ID

HGNC:13666