rat CYP24A1 Over-expression AAV

Cat. No: AAV-294490

Availability: 3-5 weeks

Name: AAV-r-CYP24A1

This is an AAV expressing Rat Cyp24a1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Cyp24a1
Gene Name: cytochrome P450, family 24, subfamily a, polypeptide 1
Gene ID: 25279
Gene Synonyms: 24-OHase; 24R-Ohase; Cyp24; P450-CC24; VITD12
ORF Size: 1545 bp
RefSeq#: BC100059
Gene Description: Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.