rat EPOR Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-293568
Availability:
3-5 weeks
Name:
AAV-r-EPOR
This is an AAV expressing Rat Epor.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Epor
- Gene Name
- erythropoietin receptor
- Gene ID
- 24336
- ORF Size
- 1524 bp
- RefSeq#
- BC089810
- Gene Description
- Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase|Function: Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
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