rat APH1A Over-expression AAV

Cat. No: AAV-292466

Availability: 3-5 weeks

Name: AAV-r-APH1A

This is an AAV expressing Rat Aph1a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Aph1a
Gene Name: aph-1 homolog A, gamma secretase subunit
Gene ID: 365872
Gene Synonyms: RGD1311546
ORF Size: 744 bp
RefSeq#: BC087081
Gene Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.