rat TRIM63 Over-expression AAV

Cat. No: AAV-290472

Availability: 3-5 weeks

Name: AAV-r-TRIM63

This is an AAV expressing Rat Trim63.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Trim63
Gene Name: tripartite motif containing 63
Gene ID: 140939
Gene Synonyms: Murf; Murf1; Rnf28
ORF Size: 1056 bp
RefSeq#: BC061824
Gene Description: E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.