rat HMGB1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-290383
Availability:
3-5 weeks
Name:
AAV-r-HMGB1
This is an AAV expressing Rat Hmgb1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Hmgb1
- Gene Name
- high mobility group box 1
- Gene ID
- 25459
- Gene Synonyms
- Ac2-008; Hmg1
- ORF Size
- 648 bp
- RefSeq#
- BC061779
- Gene Description
- DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
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