mouse ZBP1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-276503
Availability:
3-5 weeks
Name:
AAV-m-ZBP1
This is an AAV expressing Mouse Zbp1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Zbp1
- Gene Name
- Z-DNA binding protein 1
- Gene ID
- 58203
- Gene Synonyms
- 2010010H03Rik; Dai; Dlm1; mZaDLM
- ORF Size
- 1236 bp
- RefSeq#
- BC020033
- Gene Description
- Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
- UniGene ID
- Mm.116687
Related Products
Product | Cat No. |
---|---|
AAV-h-ZBP1 | AAV-228040 |
Ad-h-ZBP1 | ADV-228040 |
Ad-m-ZBP1 | ADV-276503 |
AAV-h-ZBP1-shRNA | shAAV-228040 |
AAV-m-ZBP1-shRNA | shAAV-276503 |
Ad-h-ZBP1-shRNA | shADV-228040 |
Ad-m-ZBP1-shRNA | shADV-276503 |
Control Products
Vector Biolabs
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