mouse VASH1 Over-expression AAV

Cat. No: AAV-275966

Availability: 3-5 weeks

Name: AAV-m-VASH1

This is an AAV expressing Mouse Vash1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Vash1
Gene Name: vasohibin 1
Gene ID: 238328
Gene Synonyms: AI834978; D930046M13Rik; G630009D10Rik
ORF Size: 870 bp
RefSeq#: BC086688
Gene Description: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.
UniGene ID: Mm.216101