mouse UNC13D Over-expression AAV

Cat. No: AAV-275633

Availability: 3-5 weeks

Name: AAV-m-UNC13D

This is an AAV expressing Mouse Unc13d.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Unc13d
Gene Name: unc-13 homolog D (C. elegans)
Gene ID: 70450
Gene Synonyms: 2610108D09Rik; Jinx; mFLJ00067; Munc13-4
ORF Size: 3252 bp
RefSeq#: BC141289
Gene Description: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
UniGene ID: Mm.259460