mouse UNC119 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-275629
Availability:
3-5 weeks
Name:
AAV-m-UNC119
This is an AAV expressing Mouse Unc119.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Unc119
- Gene Name
- unc-119 lipid binding chaperone
- Gene ID
- 22248
- Gene Synonyms
- D11Bhm52; HRG4; MRG4; Rg4; Rtg4; Unc119h
- ORF Size
- 723 bp
- RefSeq#
- BC001990
- Gene Description
- Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.
- UniGene ID
- Mm.284811
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