mouse UBE2M Over-expression AAV

Cat. No: AAV-275487

Availability: 3-5 weeks

Name: AAV-m-UBE2M

This is an AAV expressing Mouse Ube2m.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ube2m
Gene Name: ubiquitin-conjugating enzyme E2M
Gene ID: 22192
Gene Synonyms: 2510040H03Rik; Ubc-rs2; UBC12
ORF Size: 309 bp
RefSeq#: BC026581
Gene Description: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.
UniGene ID: Mm.196580