mouse TNFSF11 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-274722
Availability:
3-5 weeks
Name:
AAV-m-TNFSF11
This is an AAV expressing Mouse Tnfsf11.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tnfsf11
- Gene Name
- tumor necrosis factor (ligand) superfamily, member 11
- Gene ID
- 21943
- Gene Synonyms
- Ly109l; ODF; OPGL; RANKL; Trance
- ORF Size
- 951 bp
- RefSeq#
- BC125603
- Gene Description
- Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
- UniGene ID
- Mm.249221
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