mouse STIM1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-273323
Availability:
3-5 weeks
Name:
AAV-m-STIM1
This is an AAV expressing Mouse Stim1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Stim1
- Gene Name
- stromal interaction molecule 1
- Gene ID
- 20866
- Gene Synonyms
- SIM
- ORF Size
- 2058 bp
- RefSeq#
- BC021644
- Gene Description
- Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
- UniGene ID
- Mm.645
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