mouse RYK Over-expression AAV

Cat. No: AAV-271281

Availability: 3-5 weeks

Name: AAV-m-RYK

This is an AAV expressing Mouse Ryk.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ryk
Gene Name: receptor-like tyrosine kinase
Gene ID: 20187
Gene Synonyms: AW536699; ERK-3; Vik
ORF Size: 1428 bp
RefSeq#: BC032275
Gene Description: RYK may be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
UniGene ID: Mm.335391