mouse RSPO2 Over-expression AAV

Cat. No: AAV-271187

Availability: 3-5 weeks

Name: AAV-m-RSPO2

This is an AAV expressing Mouse Rspo2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rspo2
Gene Name: R-spondin 2
Gene ID: 239405
Gene Synonyms: 2610028F08Rik; AA673245; D430027K22; ftls
ORF Size: 732 bp
RefSeq#: BC156617
Gene Description: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors (By similarity).
UniGene ID: Mm.193274