mouse RAN Over-expression AAV

Cat. No: AAV-270108

Availability: 3-5 weeks

Name: AAV-m-RAN

This is an AAV expressing Mouse Ran.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ran
Gene Name: RAN, member RAS oncogene family
Gene ID: 19384
ORF Size: 651 bp
RefSeq#: BC014829
Gene Description: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2|Function: Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
UniGene ID: Mm.386831