mouse PSENEN Over-expression AAV

Cat. No: AAV-269596

Availability: 3-5 weeks

Name: AAV-m-PSENEN

This is an AAV expressing Mouse Psenen.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Psenen
Gene Name: presenilin enhancer gamma secretase subunit
Gene ID: 66340
Gene Synonyms: 1700023M09Rik; Pen-2
ORF Size: 306 bp
RefSeq#: BC024347
Gene Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
UniGene ID: Mm.86557