mouse PCSK9 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-268246
Availability:
3-5 weeks
Name:
AAV-m-PCSK9
This is an AAV expressing Mouse Pcsk9.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Pcsk9
- Gene Name
- proprotein convertase subtilisin/kexin type 9
- Gene ID
- 100102
- Gene Synonyms
- AI415265; AI747682; FH3; HCHOLA3; Narc1; PC9
- ORF Size
- 2085 bp
- RefSeq#
- BC038085
- Gene Description
- PCSK9 may be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.
- UniGene ID
- Mm.133268
Product Citations
This product is referenced in the following publications:
- Kumar S, etc (2017). Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation. Laboratory Investigation.
- LH Huang, etc (2018). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. Cell Metabolism.
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