mouse PAIP1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-268010
Availability:
3-5 weeks
Name:
AAV-m-PAIP1
This is an AAV expressing Mouse Paip1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Paip1
- Gene Name
- polyadenylate binding protein-interacting protein 1
- Gene ID
- 218693
- Gene Synonyms
- PAIP-1
- ORF Size
- 1203 bp
- RefSeq#
- BC051042
- Gene Description
- Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
- UniGene ID
- Mm.132584
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