mouse PACRG Over-expression AAV

Cat. No: AAV-267984

Availability: 3-5 weeks

Name: AAV-m-PACRG

This is an AAV expressing Mouse Pacrg.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pacrg
Gene Name: PARK2 co-regulated
Gene ID: 69310
Gene Synonyms: 1700008H23Rik
ORF Size: 726 bp
RefSeq#: BC120740
Gene Description: Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.
UniGene ID: Mm.18889