mouse NFKBIB Over-expression AAV

Cat. No: AAV-265726

Availability: 3-5 weeks

Name: AAV-m-NFKBIB

This is an AAV expressing Mouse Nfkbib.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nfkbib
Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Gene ID: 18036
Gene Synonyms: I(Kappa)B(beta); I-kappa-B-beta; IKappaBbeta; IkB; ikB-B; IKB-beta; IkBb; NF-kappa-BIB
ORF Size: 1080 bp
RefSeq#: BC021938
Gene Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
UniGene ID: Mm.220333