mouse MYO1E Over-expression AAV

Cat. No: AAV-265331

Availability: 3-5 weeks

Name: AAV-m-MYO1E

This is an AAV expressing Mouse Myo1e.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Myo1e
Gene Name: myosin IE
Gene ID: 71602
Gene Synonyms: 2310020N23Rik; 9130023P14Rik; AA407778; myosin-1e; myr 3
ORF Size: 3324 bp
RefSeq#: BC051391
Gene Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via C11orf46/ ARF7EP and ARL14.
UniGene ID: Mm.249311