mouse MRVI1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-265015
Availability:
3-5 weeks
Name:
AAV-m-MRVI1
This is an AAV expressing Mouse Mrvi1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Mrvi1
- Gene Name
- MRV integration site 1
- Gene ID
- 17540
- Gene Synonyms
- BB115629; Irag; Ris1
- ORF Size
- 2571 bp
- RefSeq#
- BC156727
- Gene Description
- Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. Recruits PRKG1 to the endoplasmic reticulum and may mediate the assembly of PRKG1 and ITPR1 in a macrocomplex. Involved in PRKG1 signaling cascade leading to inhibition of platelet activation and aggregation. Mediates also NO-dependent inhibition of calcium signaling in gastrointestinal smooth muscle contributing to NO-dependent relaxation.
- UniGene ID
- Mm.466314
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