mouse MLF1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-264686
Availability:
3-5 weeks
Name:
AAV-m-MLF1
This is an AAV expressing Mouse Mlf1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Mlf1
- Gene Name
- myeloid leukemia factor 1
- Gene ID
- 17349
- Gene Synonyms
- HLS7
- ORF Size
- 849 bp
- RefSeq#
- BC027526
- Gene Description
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
- UniGene ID
- Mm.10414
Related Products
Product | Cat No. |
---|---|
AAV-h-MLF1 | AAV-215514 |
Ad-h-MLF1 | ADV-215514 |
Ad-m-MLF1 | ADV-264686 |
AAV-h-MLF1-shRNA | shAAV-215514 |
AAV-m-MLF1-shRNA | shAAV-264686 |
Ad-h-MLF1-shRNA | shADV-215514 |
Ad-m-MLF1-shRNA | shADV-264686 |
Control Products
Vector Biolabs
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Malvern, PA 19355
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