mouse MKL1 Over-expression AAV

Cat. No: AAV-264671

Availability: 3-5 weeks

Name: AAV-m-MKL1

This is an AAV expressing Mouse Mkl1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mkl1
Gene Name: MKL (megakaryoblastic leukemia)/myocardin-like 1
Gene ID: 223701
Gene Synonyms: AMKL; Bsac; Mal; Mrtf-A
ORF Size: 2790 bp
RefSeq#: BC050941
Gene Description: Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity).
UniGene ID: Mm.439814