mouse HBEGF Over-expression AAV

Cat. No: AAV-261141

Availability: 3-5 weeks

Name: AAV-m-HBEGF

This is an AAV expressing Mouse Hbegf.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hbegf
Gene Name: heparin-binding EGF-like growth factor
Gene ID: 15200
Gene Synonyms: AW047313; Dtr; Dts; Hegfl
ORF Size: 627 bp
RefSeq#: BC089607
Gene Description: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
UniGene ID: Mm.289681