mouse FOXO1 Over-expression AAV

Cat. No: AAV-259590

Availability: Immediate

Name: AAV-m-FOXO1

This is an AAV expressing Mouse Foxo1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Foxo1
Gene Name: forkhead box O1
Gene ID: 56458
Gene Synonyms: Afxh; AI876417; FKHR; Fkhr1; Foxo1a
ORF Size: 1956 bp
RefSeq#: BC152908
Gene Description: Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence (By similarity). Triggers death of postmitotic neurons when phosphorylated by CDK1. Activates transcription of PMAIP1.
UniGene ID: Mm.29891