mouse EIF4E Over-expression AAV

Cat. No: AAV-258230

Availability: Immediate

Name: AAV-m-EIF4E

This is an AAV expressing Mouse Eif4e.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Eif4e
Gene Name: eukaryotic translation initiation factor 4E
Gene ID: 13684
Gene Synonyms: EG668879; eIF-4E; Eif4e-ps; If4e
ORF Size: 654 bp
RefSeq#: BC085087
Gene Description: Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
UniGene ID: Mm.3941