mouse DPH1 Over-expression AAV

Cat. No: AAV-257409

Availability: 3-5 weeks

Name: AAV-m-DPH1

This is an AAV expressing Mouse Dph1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dph1
Gene Name: diphthamide biosynthesis 1
Gene ID: 116905
Gene Synonyms: 2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1
ORF Size: 1314 bp
RefSeq#: BC152729
Gene Description: Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity).
UniGene ID: Mm.41496