mouse CYP1A2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-256466
Availability:
3-5 weeks
Name:
AAV-m-CYP1A2
This is an AAV expressing Mouse Cyp1a2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Cyp1a2
- Gene Name
- cytochrome P450, family 1, subfamily a, polypeptide 2
- Gene ID
- 13077
- Gene Synonyms
- CP12; Cyp1a1; P450-3
- ORF Size
- 1542 bp
- RefSeq#
- BC054827
- Gene Description
- Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
- UniGene ID
- Mm.15537
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