mouse CH25H Over-expression AAV

Cat. No: AAV-255354

Availability: 3-5 weeks

Name: AAV-m-CH25H

This is an AAV expressing Mouse Ch25h.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ch25h
Gene Name: cholesterol 25-hydroxylase
Gene ID: 12642
Gene Synonyms: AI462618; m25OH
ORF Size: 897 bp
RefSeq#: BC039919
Gene Description: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
UniGene ID: Mm.30824