mouse CASQ2 Over-expression AAV

Cat. No: AAV-254571

Availability: 3-5 weeks

Name: AAV-m-CASQ2

This is an AAV expressing Mouse Casq2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Casq2
Gene Name: calsequestrin 2
Gene ID: 12373
Gene Synonyms: AA033488; AW146219; cCSQ; Csq2; ESTM52
ORF Size: 1299 bp
RefSeq#: BC137668
Gene Description: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. The skeletal muscle isoform (CASQ1) binds around 80 Ca(2+) ions, while the cardiac isoform (CASQ2) binds approximately 60 Ca(2+) ions.
UniGene ID: Mm.15343