mouse CASP9 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-254566
Availability:
3-5 weeks
Name:
AAV-m-CASP9
This is an AAV expressing Mouse Casp9.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Casp9
- Gene Name
- caspase 9
- Gene ID
- 12371
- Gene Synonyms
- AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
- ORF Size
- 1365 bp
- RefSeq#
- BC056447
- Gene Description
- Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP)|Function: Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
- UniGene ID
- Mm.468800
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