mouse CASK Over-expression AAV

Cat. No: AAV-254545

Availability: 3-5 weeks

Name: AAV-m-CASK

This is an AAV expressing Mouse Cask.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cask
Gene Name: calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Gene ID: 12361
Gene Synonyms: DXPri1; DXRib1; LIN-2; mLin-2; Pals3
ORF Size: 2643 bp
RefSeq#: BC141292
Gene Description: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
UniGene ID: Mm.474948